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The Canadian Stem Cell Network posted an interesting item on their blog today about the relationship between stem cells and our sleep/wake cycle (circadian rhythm).
David Kent, a postdoctoral researcher at the University of Cambridge, writes about the work, published online in Nature.
The group of Salvador Aznar Benitah in Barcelona published research which links skin stem cell turnover and heterogeneity to the body’s internal clock.
The group found that when they disrupt genes that control the sleep wake cycle, they also disrupted the balance of stem cells in a dormant versus dividing state in the mouse hair follicles.
This disturbance in rhythm led to premature aging as well as an increased incidence of tumours, suggesting that we might better understand how cancers grow and progress by understanding the natural cycles our bodies go through.
http://cirmresearch.blogspot.com/

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