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Stem Cell Assays exists a little bit more than one year (one year and one month). Today I’d like to share some statistics and highlight the most frequently viewed posts in 2010. Statistical data provided by Google Analytics. Some general site usage statistics: total number of pageviews: 15 721 total number of visits: 8 020 4 877 absolute unique visitors 70-82 regular subscribers including 39 via email By Alexey Bersenev Adult stem cells do more than turn into the types of cells needed for the new organ: they orchestrate the process of assembly. Luke Masella was born with spina bifida, a birth defect that paralyzed his bladder. By the time he was 10 years old, despite various treatments, his kidneys were failing. Toxins were building up in his blood, and he had lost 25 percent of his body weight. That’s when Luke and his parents opted for a radical solution—a brand new bladder. Dental pulp stem cells expanding medical landscape and stem cell research NEW YORK, NY, Dec. 13, 2010 – The First International Conference on Dental and Craniofacial Stem Cells (ICDCSC) will take place on April 27 – 29, 2011, at the New York Academy of Sciences in New York City. This will be the first-ever assembly of the world’s most prominent scientists in the field of dental and craniofacial stem cells, as well as the emerging field of regenerative dental medicine. More than 300 participants from scientific research, industry, government agencies such as NIH and FDA will come together to encourage cross-disciplinary alliance and foster a collegial atmosphere to catalyze the advancement of dental and craniofacial stem cell research. The conference will be led by Dr. Jeremy Mao of Columbia University, Dr. Darvin Prockop of Texas A&M Medical Center, and Dr. Pamela Robey and Dr. Nadya Lumelsky of the NIH. FINDINGS: Researchers have found that by mimicking a rare genetic disorder in a dish, they can rewind the internal clock of a mature cell and drive it back into an adult stem-cell stage. RELEVANCE: Direct application for these findings is the field of tissue engineering and personalized medicine. It is conceivable that transplant patients may one day have some of their own endothelial cells extracted, reprogrammed, and then grown into the desired tissue type for implantation. Host rejection would not be an issue. Scientists primarily worked with two kinds of stem cells from animals and humans: embryonic stem cells and non-embryonic "somatic" or "adult" stem cells. The functions and characteristics of these cells will be explained in this document. Scientists discovered ways to derive embryonic stem cells from early mouse embryos nearly 30 years ago, in 1981. The detailed study of the biology of mouse stem cells led to the discovery, in 1998, of a method to derive stem cells from human embryos and grow the cells in the laboratory. These cells are called human embryonic stem cells. The embryos used in these studies were created for reproductive purposes through in vitro fertilization procedures. When they were no longer needed for that purpose, they were donated for research with the informed consent of the donor. In 2006, researchers made another breakthrough by identifying conditions that would allow some specialized adult cells to be "reprogrammed" genetically to assume a stem cell-like sta... read full post Liked by wiganfootie Regeneration has fascinated philosophers and scientists since the beginning of history. The wide but uneven distribution of regenerative capacities among multicellular organisms is puzzling, and the permissive/inhibitory mechanisms regulating this attribute in animals remain a mystery. In the first part of this lecture, I will provide a general history of regeneration research from ancient Greece to the beginning of the 20th century. Key concepts will be introduced in their appropriate historical context, and many of the unanswered questions put forward by the problem of regeneration will be discussed. |
